PUBLICATIONS

  • #Corresponding Authors
  • Sotomayor-Zárate R, Jara P, Araos P, Vinet R, Quiroz G, Renard GM, Espinosa P, Hurtado-Guzmán C, Moya PR, Iturriaga-Vásquez P, Gysling K, Reyes-Parada M (2014) “Improving amphetamine therapeutic selectivity: N,N-dimethyl-MTA has dopaminergic effects and does not produce aortic contraction” Basic Clin Pharmacol Toxicol. 114(5): 395-9. doi: 10.1111/bcpt.12168.
  • #Moya PR, Wendland JR, Andrews AM, Rubenstein L, Timpano KC, Heiman GA, Tischfield JA, King RA, Ramamoorthy S, McMahon F, Murphy DL (2013) “Common and rare alleles of the serotonin transporter gene, SLC6A4, associated with Tourette disorder” Movement Disorders. 28(9): 1263-70 DOI: 10.1002/mds.25460
  • Murphy DL, Moya PR, Fox MA, Rubenstein LM, Wendland JR, Timpano KR (2013) “Anxiety and Affective Disorder Comorbidity Related to Serotonin and other Neurotransmitter Systems: Obsessive-compulsive Disorder (OCD) as an Example of Overlapping Clinical and Genetic Heterogeneity Philosophical Transactions of the Royal Society B: Biological Sciences, 368 (1615). DOI:10.1098/rstb.2012.0435 (REVIEW)
  • #Moya PR, Dodman NH, Timpano KC, Rubenstein L, Rana Z, Fried R, Tischfield JA, Heiman JA, King RA, Ginns E, Wendland JR (2013) “Neuronal Cadherin (CDH2) Gene Missense Variants in Specific Obsessive-Compulsive Disorder and Tourette Syndrome Phenotypes” European Journal of Human Genetics, 21(8): 850-4. DOI: 10.1038/ejhg.2012.245
  • #Moya PR, Wendland JR, Salemme J, Fried R, Murphy DL (2013) “miR15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells” International Journal of Neuropsychopharmacology, 16: 621–629.
  • Stewart SE, Mayerfeld C, Arnold PD, Crane JR, O’Dushlaine C, Fagerness JA, Scharf JM, Kassam F, Moya PR, Wendland JR, Delorme R, et al. (2013) “Meta-Analysis of association between obsessive-compulsive disorder and the 3’ region of neuronal glutamate transporter gene SLC1A1” American Journal of Medical Genetics part B: Neuropsychiatric Genetics, 162: 367-379
  • Fox MA, Panessiti M, Moya PR, Tolliver TJ, Chen K, Shih JC, Murphy DL (2012) “Mutations in monoamine oxidase (MAO) genes in mice lead to hypersensitivity to serotonin enhancing drugs: implications for drug side effects in humans” The Pharmacogenomics Journal, 13(6): 551-7. DOI: 10.1038/tpj.2012.35.
  • Sotomayor-Zárate R, Quiroz G, Araya KA, Abarca J, Ibáñez MI, Montecinos A, Guajardo C, Núñez-Vicanco G, Fierro A, Moya PR, Iturriaga-Vásquez P, Gómez-Molina C, Gysling K, Reyes-Parada M (2012) “4-Methylthioamphetamine Increases Dopamine in the Rat Striatum and has Rewarding Effects In Vivo” Basic and Clinical Pharmacology and Toxicology, 111(6):371-9. DOI: 10.1111/j.1742-7843.2012.00926.x.
  • Khaibullina A, Kenyon N, Guptill V, Quezado M, Koziol D, Wesley R, Moya PR, Zhang Z, Saha A, Mukherjee AB, Quezado ZMN (2012) “In a model of Batten disease, palmitoyl protein thioesterase-1 deficiency is associated with brown adipose tissue and thermoregulation abnormalities” PLoS One, 7(11):e48733.
  • Liu X, Cannon DM, Akula N, Moya PR, Knudsen GM, Arentzen TE, Steele J, Laje G, Drevets WC, McMahon FJ (2011) “A non-synonymous polymorphism in galactose mutarotase (GALM) is associated with serotonin transporter binding potential in the human thalamus: results of a genome-wide association study” Molecular Psychiatry 16(6):584-5.
  • Murphy DL and Moya PR (2011) “Human Serotonin Transporter Gene (SLC6A4) variants: Their contributions to understanding pharmacogenomic and other functional G x G and G x E differences in health and disease” Current Opinions in Pharmacology, 11(1):3-10. (REVIEW)
  • #Moya PR, Jensen CL, Fox MA, French H, Wendland JR and Murphy DL (2011) “Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice” BMC Pharmacology 11:3.
  • #Moya PR, Murphy DL, McMahon FJ and Wendland JR (2010) “Increased gene expression of Diacylglycerol Kinase Eta in Bipolar Disorder” International Journal of Neuropsychopharmacology 13(8):1127-1128
  • Omata N, Chiu CT, Moya PR, Leng Y, Chiu C, Wang Z, Hunsberger J, Leeds P, Chuang DM (2011) “Lentivirally mediated GSK-3β silencing in the hippocampal dentate gyrus induces antidepressant-like effects in stressed mice ” International Journal of Neuropsychopharmacology 14(5):711-717
  • Wendland JR, Moya PR, Timpano K, Anavitarte A, Kruse M, Wheaton M, Ren-Patterson R, Murphy DL (2009) “A haplotype containing quantitative trait loci for SLC1A1 gene expression is associated with obsessive-compulsive disorder” Archives of General Psychiatry 66(4):408-16.
  • (* first co-author) Wendland JR*,Moya PR*, Kruse MR, Ren-Patterson RF, Jensen CL, Timpano KR and Murphy DL (2008) “A novel, putative gain-of-function haplotype at SLC6A4 associates with obsessive-compulsive disorder” Human Molecular Genetics 17(5):717-23.
  • Murphy, DL, Fox MA, Timpano KR, Moya PR, Ren-Patterson R, Andrews A, Holmes, A, Wendland JR, Lesch KP (2008) “How the serotonin story is being rewritten by new gene-based discoveries principally related to SLC6A4, the serotonin transporter gene, whose functions influence the entire serotonin system” Neuropharmacology 55:932-960. (REVIEW)
  • Gobbi M, Funicello M, Gerstbrein K, Holy M, Moya PR, Sotomayor R, Forray MI, Gysling K, Paluzzi S, Bonanno G, Reyes-Parada M, Sitte HH, Mennini T (2008) “N,N-dimethyl-thioamphetamine and methylthio-amphetamine, two non-neurotoxic substrates of 5-HT transporters, have scant in vitro efficacy for the induction of transporter-mediated 5-HT release and currents” Journal of Neurochemistry 105(5):1770-80.
  • Moya PR, Berg KA, Gutierrez-Hernandez MA, Saez-Briones P, Reyes-Parada M, Cassels BK, Clarke WP (2007) “Functional Selectivity of Hallucinogenic Phenethylamine and Phenylisopropylamine Derivatives at Human 5-HT2A and 5-HT2C Receptors” Journal of Pharmacology and Experimental Therapeutics 321(3):1054-61.
  • Valdecantos P, Briones R, Moya P, Germain A, and Huidobro-Toro JP (2003) “Pharmacological identification of P2X(1), P2X(4) and P2X(7) nucleotide receptors in the smooth muscles of human umbilical cord and chorionic blood vessels” Placenta 24(1):17-26.
  • Acuña-Castillo C, Villalobos C, Moya PR, Sáez P, Cassels BK, and Huidobro-Toro JP (2002) “Differences in potency and efficacy of a series of phenylisopropylamine / phenylethylamine pairs at 5-HT2A and 5-HT2C receptors” British Journal of Pharmacology 136: 510-519.

  • Murphy DL, Moya PR, Wendland JR and Timpano KR (2012)“Genetic contributions to obsessive-compulsive disorder (OCD) and OCD-related disorders”, en Principles of Psychiatric Genetics, J. Nurnberger & W. Berrettini Eds, Cambridge University Press, Cambridge, UK. Capitulo 11, pp 121-133. ISBN: 0521896495

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