Our studies search for genetic variability that increases the susceptibility for OCD, Tourette syndrome, epilepsy and schizophrenia. We detect single-nucleotide variations; perform genotyping analysis and functional studies for genetic variants. We are also interested in epigenetic and transcriptome analyses. We follow both classic targets at serotonin and dopamine neurotransmitter systems, as well as novel candidates suggested by large genome-wide association studies (GWAS).
Some Illustrations from National Institute of Mental Health, National Institutes of Health, Department of Health and Human Services